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ALF

What is Acute Liver Failure (ALF)?

Acute Liver Failure (ALF) is a rare, life-threatening illness where the liver rapidly loses function within days or weeks in a previously healthy person. Causes include:

  • Drug-Induced Liver Failure
  • Viral Hepatitis
  • Metabolic Disorders

At Liver Surgeons, Delhi’s premier ALF treatment center, we provide emergency care, advanced therapies, and transplants to reverse liver damage before it becomes fatal.

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Acute Liver Failure

Life-saving dual organ transplantation with 80% 5-year survival rates

Symptoms of ALF

Seek immediate medical help if you notice:

  • Sudden jaundice (yellow skin/eyes)
  • Confusion, agitation, or coma (hepatic encephalopathy)
  • Severe nausea/vomiting
  • Bleeding tendencies (nosebleeds, bruising)
  • Swollen abdomen (ascites)

ALF Treatment Options

1. Emergency Stabilization

  • N-Acetylcysteine (NAC): Antidote for paracetamol overdose treatment (even if ingestion is uncertain).
  • Plasma Exchange: Removes toxins and buys time for liver recovery.
  • Intensive Care for ALF: 24/7 monitoring of brain pressure, blood clotting, and organ function.

2. Liver Transplant for ALF

  • Criteria: King’s College/PALF (pediatric) guidelines determine transplant urgency.
  • Process: Prioritized organ allocation via NOTTO for ALF patients.
  • Outcomes75% survival rate with timely transplants at our Delhi center.

3. Pediatric Acute Liver Failure

  • Causes: Metabolic errors (e.g., galactosemia), viral infections, or unknown triggers.

Care: Dedicated pediatric hepatologists and child-sized life-support systems.

Why Choose Liver Surgeon for ALF?

  • India’s Leading ALF Program: 200+ ALF cases are managed annually, with 60% survival without transplant.
  • Rapid Response Protocol:
    • Same-Day Diagnosis: FibroScan® + ammonia levels.
    • Emergency Transplants: Average wait time of 72 hours for matched organs in Delhi.
  • Advanced ICU:
    • Intracranial pressure monitoring to prevent brain swelling.
    • CRRT (Continuous Renal Replacement Therapy) for kidney support.

Pan-India Reach: Air ambulances transport critical patients from across India.

ALF Treatment Process

Step 1: Emergency admission via a 24/7 helpline.

Step 2: Stabilization with NAC, antibiotics, and clotting factors.

Step 3: Transplant evaluation (MELD score ≥35 qualifies for priority).

Step 4: Transplant surgery or medical management for recoverable cases.

SKS & Complications

Risk Our Intervention
Cerebral Edema Mannitol, hypertonic saline, sedation
Infections Broad-spectrum antibiotics
Multi-Organ Failure CRRT, ventilator support
Bleeding Vitamin K, platelet transfusions

Success Stats:

  • 80% pediatric ALF survival with early intervention.
  • 50% lower transplant need for drug-induced ALF cases.

Every Minute Matters in ALF – Don’t Wait, Call Now!

Testimonials

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CRITICAL CARE QUESTIONS

Acute Liver Failure FAQs

Yes! 30–40% recover with emergency NAC therapy or plasma exchange if treated within 48 hours of symptom onset. Our Delhi ICU achieves 45% survival rates through rapid intervention protocols.

In India, viral hepatitis (HEV) and metabolic disorders account for 60% of cases. We recommend immediate referral to our pediatric ALF specialists who achieve 70% recovery rates through targeted therapies.

₹8–15 lakhs for medical management (plasma exchange, medications). ₹35–45 lakhs for transplants. Our financial counselors secure insurance approvals in <24 hours and offer EMI options.

Absolutely not. Our hepatologists prescribe safer alternatives like ibuprofen or tramadol post-recovery. All ALF survivors receive a customized medication safety card listing prohibited drugs.

High-risk medications include:
Antibiotics: Isoniazid, sulfa drugs
Anticonvulsants: Valproate, phenytoin
Herbals: Kava, green tea extract

Our toxicology team uses mass spectrometry to identify triggers within 6 hours.

Non-transplant cases: 3–6 months with biweekly LFT monitoring
Transplant recipients: 6–12 months including:
• Immunosuppression adjustments
• Nutritional rehab
• Psychosocial support
Our Delhi rehab program achieves 90% functional recovery rates.

ALF:
• Sudden (days/weeks)
• Healthy livers
• Toxins/viruses cause
CLF:
• Years of damage
• Cirrhosis present
• Managed long-term

ALF requires emergency ICU care; CLD focuses on slowing progression.

Key prevention strategies:
1. Paracetamol: Never exceed 4g/day
2. Vaccination: Hepatitis A/B essential
3. Herbal caution: Consult our specialists first
4. High-risk groups: Pregnant women get preemptive LFTs

Our Delhi clinic offers free prevention workshops monthly.