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Fatty Liver

What is Fatty Liver Disease?

Fatty liver disease happens when excess fat builds up in liver cells, categorized into

Key Risk Groups

  • MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease): Linked to obesity, diabetes, or metabolic syndrome.
  • NASH (Non-Alcoholic Steatohepatitis): A severe form causing inflammation and fibrosis.
  • Left untreated, it can progress to advanced fibrosis, cirrhosis, or liver failure.
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Fatty Liver Disease

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Causes & Symptoms

  • Key Causes:
    • Obesity: Primary driver of MASLD (60–80% of cases).
    • Insulin resistance, high cholesterol, and sedentary lifestyle.

Symptoms: Fatigue, abdominal discomfort, and jaundice (in advanced stages).

Advanced Diagnosis

  • MASLD/NASH Diagnosis:
    • FibroScan®: Non-invasive staging of liver stiffness and fat content.
    • MRI Elastography: Detects early fibrosis.
    • Liver Biopsy for MASH: Confirms inflammation and fibrosis severity.

Blood Tests: ALT/AST ratios, lipid profiles, and HbA1c.

Fatty Liver Disease Treatment

1. Reversing Fatty Liver Damage

  • Weight Loss: 5–10% reduction reverses early-stage MASLD.
  • Medications: Vitamin E, pioglitazone (for NASH), and GLP-1 agonists (for obesity-linked cases).

2. NASH Cirrhosis Management

  • Lifestyle Changes: Low-carb diets, aerobic exercise, and alcohol avoidance.
  • Monitoring: Regular FibroScan® to track fibrosis progression.
  • Transplant Evaluation: For decompensated cirrhosis (MELD score ≥15).

3. Lifestyle Interventions

  • Diet: A Mediterranean diet rich in antioxidants.

Exercise: 150+ minutes/week of moderate activity.

Why Choose Liver Surgeon in Delhi?

  • Dr. Ashish George: Leading fatty liver specialist with 15+ years’ expertise in reversing MASLD/NASH and managing advanced fibrosis.
  • Cutting-Edge Tools:
    • India’s first NAFLD FibroSuite™ for precise staging.
    • Genetic testing for personalized therapy.
  • Proven Outcomes:
    • 90% success in reducing liver fat with structured programs.
    • 50% lower cirrhosis risk for NASH patients under our care.

Holistic Support: Nutritionists, endocrinologists, and mental health counselors.

Success Stats:

  • 80% of patients achieve 10% weight loss in 6 months.
  • 70% reduction in liver fat for MASLD cases.

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Fatty Liver Disease FAQs

Yes! Early-stage MASLD (steatosis) is fully reversible with lifestyle changes. Even NASH patients show significant improvement with 7-10% weight loss and targeted medications under medical supervision.

Excess body fat triggers insulin resistance, causing the liver to overproduce and store fat. Our Delhi clinic's integrated program combines:
• Medical weight management
• MASLD-specific nutrition plans
• Exercise physiology
to achieve both weight loss and liver health improvement.

Dr. Ashish George recommends biopsies only when:
• FibroScan® results are inconclusive
• Suspected advanced fibrosis (F3-F4)
• Evaluating for clinical trials
Our Delhi center uses transient elastography for 90% of cases, minimizing patient discomfort.

Our liver nutritionists recommend:
• Mediterranean-style eating pattern
• 25-30g fiber daily from whole grains
• Lean proteins (plant-based preferred)
• Healthy fats (nuts, olive oil, fatty fish)
• Strict avoidance of:
  - Sugary beverages
  - Processed snacks
  - Trans fats

Dr. Ashish George's therapeutic approach:
Early NASH:
• Vitamin E (800IU/day)
• Pioglitazone (30mg/day)
Advanced fibrosis:
• GLP-1 agonists (semaglutide)
• FXR agonists when available
All treatments are combined with lifestyle modification programs at our Delhi center.

Yes. Patients with NASH cirrhosis have 2-12% annual risk of HCC. Our surveillance protocol includes:
• Quarterly ultrasound + AFP
• Biannual FibroScan®
• MRI for high-risk cases
Early detection at our India clinics improves 5-year survival to >70%.

Genetic factors contribute:
• PNPLA3 variant increases risk 3-fold
• TM6SF2 affects lipid metabolism
Our Delhi clinic offers:
• Genetic testing for high-risk families
• Personalized prevention plans
• Family screening programs
Lifestyle modifications remain key regardless of genetic risk.

Metabolic surgery benefits include:
• 60-80% excess weight loss
• NASH resolution in 85% of cases
• Fibrosis improvement in 40%
Dr. Ashish George collaborates with bariatric surgeons to:
• Select appropriate candidates (BMI >35 with NASH)
• Optimize pre-op liver health
• Provide post-surgical metabolic monitoring